Chromatographic purification of a cytotoxic chloroform extract of Formosan soft coral Sinularia granosa (collected in Green Island) led to the isolation of two known norcembrane norditerpenoids, (1R*, 5S*, 8R*, 10S*, 11R*)–11
–hydroxy–1–isopropenyl–8–methyl—3, 6—dioxo—5, 8—epoxy—cyclotetradec—12—ene—10, 12－carbolactone (45) and (1R*, 5S*, 8R*, 10S*, 11S*)—11—hydroxy—1—isopropenyl—8—methyl—3, 6—dioxo—5, 8—epoxy—cyclotetradec—12—ene—10, 12－carbolactone (46).
