This thesis consists of five Chapters. The first Chapter is an introduction, which includes motive, research scope, approaching method and procedure. The second chapter makes the comparisons and discussions based on domestic disaster emergency response system at present.Chapter three discusses the comparisons of rescuing capacity of Science Park Administration at present with the one of Hsinchu City Government to realize the rescuing condition and load degree to construct and promote the works of disaster prevention and response of Science Park Administration accordingly in the future. Chapter four proposes the possible emergency response structure for Science-based Industrial Park.Finally, the conclusions and suggestions, which could be the refered to promote the disaster emergency system of Hsinchu Science-based Industrial Park from this research are given in Chapter Five.